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Prevnar: A Vaccine for Pneumococcal Infections in Infants

Brand Name Drug: Prevnar Active Ingredient Drug: pneumococcal 7-valent conjugate vaccine (diphtheria CRM197 protein) Indication: Prevention of invasive pneumococcal disease in infants and toddlers Company Name: American Home Products Corporation (Wyeth Lederle Vaccines division) Availability: Approved by the…

Targretin: Help Patients with Cutaneous T-Cell Lymphoma

Brand Name Drug: Targretin Active Ingredient Drug: bexarotene Indication: Treatment of cutaneous manifestations of early and advanced cutaneous T-cell lymphoma in patients refractory to at least one prior systemic therapy Company Name: Ligand Pharmaceuticals Incorporated Availability: Approved by…

Doxil for Metastatic Ovarian Cancer

Brand Name: Doxil Active Ingredient: doxorubicin HCl liposome injection Indication: Treatment of metastatic ovarian cancer in patients with the disease that is refractory to both paclitaxel- and platinum-based chemotherapy Company Name: ALZA Pharmaceuticals Availability: Not approved for marketing…

Raptiva (Efalizumab) – drug for the treatment of plaque psoriasis

Trade Name Drug: Raptiva Generic Name Drug: Efalizumab Company: Genentech Indication/Use: Plaque Psoriasis Approval Date: Oct. 28, 2003 FDA Class: B Development Efalizumab (Raptiva), a humanized therapeutic antibody designed to selectively and reversibly block the activation, reactivation, and…

Remicade Plus: Drug for Rheumatoid Arthritis

Brand Name: Remicade Active Ingredient: infliximab Indication: Treatment of rheumatoid arthritis when administered with methotrexate Company Name: Centocor, Inc. Availability: Approved for this indication in November 1999 (had already been approved for treating Crohn’s disease) Introduction Remicade (infliximab),…

Ferrlecit for Iron Deficiency

Brand Name: Ferrlecit Active Ingredient: sodium ferric gluconate complex sucrose injection Indication: iron deficiency in patients undergoing chronic hemodialysis who are receiving supplemental erythropoietin therapy Company Name: Schein Pharmaceutical, Inc. Introduction Ferrlecit is used to increase the total…

Pletal for the Treatment of Intermittent Claudication

Brand Name: Pletal Active Ingredient: cilostazol Approved uses: the reduction of symptoms of intermittent claudication, as indicated by an increase in walking distance Dosage Form(s): Tablets (50 mg and 100 mg) Company Name: Otsuka America Pharmaceutical, Inc. Availability:…

Novantrone: Managing Multiple Sclerosis

Brand Name Drug: Novantrone Active Ingredient Drug: mitoxantrone Indication: Reduce the number of relapses and slow down disease progression in Multiple Sclerosis (MS) Company Name: Immunex Corporation Introduction Immunex submitted an NDA – New Drug Application – for…

Sonata: the Treatment of Insomnia

Brand Name: Sonata Active Ingredient: zaleplon Indication: Treatment of short-term insomnia Company Name: Wyeth-Ayerst Laboratories, Inc. Availability: Approved for marketing in the US on 16 August 1999 Introduction According to the National Sleep Foundation, insomnia affects nearly 83…

Exelon: Drug for Alzheimer’s Disease

Brand Name Drug: Exelon Active Ingredient Drug: rivastigmine tartrate Indication: Treatment of mild to moderate Alzheimer’s disease Company Name: Novartis Pharmaceuticals Corporation Availability: Approved by the FDA on April 24, 2000 Introduction Some 4 million Americans are afflicted…