GERD

Diagnosis of Gastroesophageal Reflux Disease

Clinical presentation The prevalence of heartburn, the most common clinical manifestation of Gastroesophageal reflux, is difficult to determine. Most people consider this sensation normal and do not seek medical attention. It is estimated that at least one third…

Gastroesophageal Reflux Disease. Complications. Diagnosis

Key Clinical / Diagnostic Terms Barrett’s esophagus — A change in cell shape of the epithelial lining to columnar; associated with increased incidence of esophageal adenocarcinoma Bernstein test — A provocative test in which acid is infused into…

Gastroesophageal Reflux Disease. Surgery. Conclusion

Surgical therapy is generally undertaken when medical therapy is ineffective or not desired by the patient. Surgery to improve the barrier between the stomach and esophagus is an appropriate option if the patient has a mechanically defective cardia…

Management of GERD: Treatment Approach

OTC (over-the-counter) antacids and acid suppressants are appropriate initial patient-directed therapy for mild heartburn.Patients should be advised to take these agents when symptoms arise or if they anticipate symptoms after an activity that can promote heartburn (eg, a…

Management of GERD: Prescription Therapies

Proton pump inhibitors (PPIs) Prescription therapies aimed at reducing acid secretion in patients with gastroesophageal reflux disease (GERD) are H2RAs and PPIs. Ample clinical evidence supports the superiority of acid suppression with proton pump inhibitors (PPIs) over other…

Gastroesophageal reflux disease

Description of Medical Condition Reflux of gastroduodenal contents into the esophagus, larynx or lungs with or without esophageal inflammation System(s) affected: Gastrointestinal Genetics: N/A Incidence/Prevalence in USA: 65% of adults have suffered heartburn; 24% have had symptoms for…

Management of GERD: Treatment Goals

Treatment Goals Symptom relief should be the primary concern when selecting a strategy to manage gastroesophageal reflux disease (GERD). Healing erosive esophagitis is another important outcome in GERD, since reversing esophageal injury can prevent long-term complications. Speed of…

Gastroesophageal Reflux Disease. Treatment. Lifestyle Modifications

Treatment Resolving symptoms and maintaining remission are primary goals of therapy (Table 3). Other therapeutic goals include esophageal healing in esophagitis, and preventing complications. To achieve these results, educating the patient is fundamentally important. The pharmacist and the…

Management of GERD: Diagnosis

Many diagnostic tests and procedures can be performed to confirm gastroesophageal reflux disease (GERD) and establish disease severity, such as endoscopy, barium swallow tests, and ambulatory pH monitoring. However, pharmacists are often the first health professionals that patients…

Gastroesophageal Reflux Disease. Pharmacologic Treatment

If lifestyle changes do not effectively reduce symptoms, pharmacologic therapy is warranted. Pharmacologic therapy is designed to decrease the amount of acid that refluxes from the stomach back into the esophagus, increase gastrointestinal motility, or make the refluxed…