GERD

Complications of Gastroesophageal Reflux Disease

Strictures An esophageal peptic stricture is thought to result from fibrosis when inflammation and injury extend below the mucosa as a consequence of chronic Gastroesophageal reflux. Up to 11% of patients with Gastroesophageal reflux disease seem to develop…

Treatment of Gastroesophageal Reflux Disease

Gastroesophageal reflux disease is a chronic disorder. It is important to educate the patients to modify their lifestyle and habits that may promote Gastroesophageal reflux and encourage them to adopt new habits that will bring long-term beneficial results….

Management of GERD: OTC Pharmacologic Interventions

Acid-suppressive therapy is the mainstay of treatment for gastroesophageal reflux disease (GERD). Antacids, histamine2 receptor antagonists (H2RAs) and proton pump inhibitors (PPIs) can be used in patients with GERD. Prokinetic agents are of limited utility due to inadequate…

Diagnosis of Gastroesophageal Reflux Disease

Clinical presentation The prevalence of heartburn, the most common clinical manifestation of Gastroesophageal reflux, is difficult to determine. Most people consider this sensation normal and do not seek medical attention. It is estimated that at least one third…

Gastroesophageal Reflux Disease. Complications. Diagnosis

Key Clinical / Diagnostic Terms Barrett’s esophagus — A change in cell shape of the epithelial lining to columnar; associated with increased incidence of esophageal adenocarcinoma Bernstein test — A provocative test in which acid is infused into…

Gastroesophageal Reflux Disease. Surgery. Conclusion

Surgical therapy is generally undertaken when medical therapy is ineffective or not desired by the patient. Surgery to improve the barrier between the stomach and esophagus is an appropriate option if the patient has a mechanically defective cardia…

Management of GERD: Treatment Approach

OTC (over-the-counter) antacids and acid suppressants are appropriate initial patient-directed therapy for mild heartburn.Patients should be advised to take these agents when symptoms arise or if they anticipate symptoms after an activity that can promote heartburn (eg, a…

Management of GERD: Prescription Therapies

Proton pump inhibitors (PPIs) Prescription therapies aimed at reducing acid secretion in patients with gastroesophageal reflux disease (GERD) are H2RAs and PPIs. Ample clinical evidence supports the superiority of acid suppression with proton pump inhibitors (PPIs) over other…

Gastroesophageal reflux disease

Description of Medical Condition Reflux of gastroduodenal contents into the esophagus, larynx or lungs with or without esophageal inflammation System(s) affected: Gastrointestinal Genetics: N/A Incidence/Prevalence in USA: 65% of adults have suffered heartburn; 24% have had symptoms for…

Management of GERD: Treatment Goals

Treatment Goals Symptom relief should be the primary concern when selecting a strategy to manage gastroesophageal reflux disease (GERD). Healing erosive esophagitis is another important outcome in GERD, since reversing esophageal injury can prevent long-term complications. Speed of…