Drugs

Psychotropic Drugs in Children: Thioridazine (Mellaril)

Table 4 Prescribing Information for Thioridazine (Mellaril ®) Optimum Dosage 1-3 mg/kg/day 20-200 mg/day Not recommended under 2 years of age Starting dose 10-25 mg b.i.d. Drug Interactions CNS depressants Antacids decrease absorption Anticholinergics Anticonvulsants increase risk of…

Mental Distress Increases Risk of Hip Fracture

A recent report suggests that loneliness, depression, and other emotional complaints are associated with an increased risk of hip fracture in older women. Researchers at the National Institute of Public Health in Oslo, Norway, interviewed more than 18,000…

Psychotropic Drugs in Children: Indications

The physician should choose the one most appropriate medication. Current indications for the use of psychotropic medications in children and adolescents can be summarized briefly (Table l). The listing in Table 1 is by no means an exhaustive…

Non-steroidal Anti-inflammatory Drugs (NSAIDs): Conclusion

The British Columbia Drug Usage Review program has focused on the use of non-steroidal anti-inflammatory drugs (NSAIDs) and other target medications for a number of years. The program promotes rational prescribing for all age groups, with special emphasis…

Opioid overdose

An 18-year-old man is brought into the emergency department after being found on the street unresponsive. He is lethargic and does not answer questions. He has been given 1 ampule of Dextrose intravenously without result. On examination, his…

Nonsteroidal Anti-Inflammatory Drugs: Results, Analysis

Results Searches found 86 reports (10160 patients) that met inclusion criteria, 76 of which had dichotomous pain outcomes, including three unpublished reports from a pharmaceutical company. For acute conditions, 37 placebo-controlled trials were analyzed. All but one of…

Top 15 Global Pharmaceutical Products – 2008 Rank

2008 rank (US$) 2008 Sales (US$ MN) % Growth 2008 (LC$) Lipitor 1 $ 13,655 (0.9) Plavix 2 $ 8,634 16.9 Nexium 3 $ 7,842 7.8 Seretide 4 $ 7,703 7.0 Enbrel 5 $ 5,703 5.6 Seroquel 6…

NSAIDs

A 16-year-old female comes to the physician’s office because of menstrual cramps. She had menarche at age 13. Her menses lasts for 4-5 days, and she has 28-day cycles. For the first 2-3 days of her menses she…

Psychotropic Drugs in Children: Responding to Parents Questions

Freeman recommends that the physician should be prepared for a potential barrage of questions by the enlightened parent consumer. Such questions may include any or all of the following: • How do drugs change behaviour? • My child…

Opioid overdose: Questions – Answers

Questions [1] Morphine produces analgesia through which of the following actions? A. Activation of neuronal adenylyl cyclase B. Increased prejunctional neurotransmitter release C. Reduction of postjunctional neuronal potassium conductance D. Reduction of prejunctional neuronal calcium conductance [2] Which…