Reglan (Metoclopramide)

Reglan (Metoclopramide) is a crucial medication in managing various gastrointestinal issues. Whether you’re a patient or just curious, this comprehensive guide provides valuable insights into Reglan’s general information, ingredients, proper usage, potential interactions, side effects, overdose risks, and storage tips.

Reglan, also known by its generic name Metoclopramide, belongs to a class of medications called prokinetics. It increases the contractions in the stomach and intestines, promoting food movement through the digestive system. Typically prescribed to alleviate symptoms of conditions such as gastroesophageal reflux disease (GERD), diabetic gastroparesis, and nausea/vomiting caused by chemotherapy, Reglan can offer relief to those grappling with gastrointestinal challenges.

Ingredients

The active ingredient in Reglan is Metoclopramide hydrochloride. It’s essential to be aware of this component, especially if you have known allergies or sensitivities. If you have concerns about specific ingredients, consult your healthcare provider before starting the medication.

How to Take

Reglan is usually taken orally, either with or without food. Follow your healthcare provider’s instructions carefully, and never exceed the prescribed dosage. If you miss a dose, take it as soon as you remember unless it’s almost time for the next scheduled dose. In that case, skip the missed dose and continue your regular dosing schedule.

Interactions

It’s crucial to inform your healthcare provider about all medications, supplements, and herbal products you are currently taking. Reglan may interact with certain medications, such as narcotics, antipsychotics, and drugs that affect dopamine levels. These interactions can influence the effectiveness of Reglan or increase the risk of side effects.

Side Effects

While many people tolerate Reglan well, being aware of potential side effects is essential. Common side effects include drowsiness, restlessness, and nausea. However, more severe side effects may occur, such as involuntary movements, muscle stiffness, and mental/mood changes. If you experience any concerning side effects, contact your healthcare provider promptly.

Overdose

In the rare event of an overdose, seek immediate medical attention. Symptoms may include confusion, seizures, or loss of consciousness. Be mindful of your prescribed dosage; never self-adjust without consulting your healthcare provider.

Storage

Store Reglan at room temperature, away from light and moisture. Keep it out of reach of children and pets. Do not store it in the bathroom. Proper storage ensures the medication remains effective and safe for use.

Drug Approvals

(British Approved Name, rINN)

Synonyms: Metoclopramida; Metoclopramidum; Metoklopramid; Metoklopramidas; Metoklopramidi

BAN: Metoclopramide

INN: Metoclopramide [rINN (en)]

INN: Metoclopramida [rINN (es)]

INN: Métoclopramide [rINN (fr)]

INN: Metoclopramidum [rINN (la)]

INN: Метоклопрамид [rINN (ru)]

Chemical name: 4-Amino-5-chloro-N-(2-diethylaminoethyl)-2-methoxybenzamide

Molecular formula: C14H22ClN3O2 =299.8

CAS: 364-62-5

ATC code: A03FA01

Pharmacopoeias. In China, Europe, and Japan.

European Pharmacopoeia, 6th ed. (Metoclopramide). A white or almost white, fine powder. It exhibits polymorphism. Practically insoluble in water, sparingly soluble to slightly soluble in alcohol and dichloromethane.

Metoclopramide Hydrochloride

(British Approved Name Modified, US Adopted Name, rINNM)

Drug Nomenclature

Synonyms: AHR-3070-C; DEL-1267; MK-745; Metoclopramide, hidrocloruro de; Metoclopramide Hydrochloridum; Metoclopramide Hydrochloridum Monohydricum; Metoklopramid-hidroklorid; Metoklopramid-hydrochloride monohydrát; Metoklopramidhydroklorid; Metoklopramidihydrokloridi; Metoklopramido hidrochloridas

BAN: Metoclopramide Hydrochloride [BANM]

USAN: Metoclopramide Hydrochloride

INN: Metoclopramide Hydrochloride [rINNM (en)]

INN: Hidrocloruro de metoclopramide [rINNM (es)]

INN: Métoclopramide, Chlorhydrate de [rINNM (fr)]

INN: Metoclopramide Hydrochloridum [rINNM (la)]

INN: Метоклопрамида Гидрохлорид [rINNM (ru)]

Molecular formula: C14H22ClN3O2,HCl,H2O =354.3

CAS: 7232-21-5 (anhydrous metoclopramide hydrochloride); 54143-57-6 (metoclopramide hydrochloride monohydrate); 2576-84-3 (anhydrous metoclopramide dihydrochloride)

ATC code: A03FA01

Read code: y027o