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ALENDRONATE

ALENDRONATE (A LEN droe nate)

Other Names for this Medication (Brand Names)

Adronat, Alendros, Arendal, Apo-Alendronate, Fosamax, Novo-Alendronate, Onclast

Appearance

Oral Tablets: White round uncoated (5mg), White oval wax polished (10mg), White oval uncoated (35mg), White triangular uncoated (40mg), White oval uncoated (70mg) tablets (Merck Frosst Brand). Other brands may have different appearances. Oral Solution: Clear, colorless oral solution with a raspberry flavour (70mg/bottle)

Why this Medication is Used

Alendronate is used to prevent osteoporosis in women who have undergone menopause. Alendronate is also used to treat osteoporosis in men and women who have developed the disease due to natural causes or drugs. Alendronate is also used to treat Paget’s disease of the bone. Alendronate is in a class of medications called bisphosphonates. It works by preventing bone breakdown and increasing bone density (thickness) to make bones stronger and less likely to break.

How do you take this Medication

Oral Tablets or Solution: Tablets may be taken once a day or once a week, depending on the dose ordered, with a full glass of water (6-8oz) first thing in the morning. After taking Alendronate, wait at least 30 minutes before taking any food, beverage, or other medication of the day, including antacids, calcium supplements and vitamins. Alendronate is most effective only if taken when your stomach is empty. You should not chew or suck on the tablets; swallow them whole. Do not lie down for at least 30 minutes after taking this medication. Drink at least a quarter of a cup (2 oz or 60ml) of water after taking the oral solution.

Precautions

• If you are pregnant or breast-feeding you should not be taking Alendronate. You should not take Alendronate if you have stomach or intestine problems, or kidney disease. Tell your doctor if you have had trouble with any of these problems and if you have trouble standing or sitting upright for at least 30 minutes.

• Alendronate should not be taken at the same time as any other medication. DO NOT take antacids, or any other prescription (or over the counter) medications containing calcium, iron, magnesium, or aluminum at the same time as you take Alendronate tablets. If you must take other medications, they should be taken at least 1 to 2 hours after Alendronate is taken. Check with your doctor or pharmacist if you are not sure on how and when to take your medications.

• Your Doctor may ask you to take a calcium and vitamin D supplement in addition to Alendronate. If you do, remember to take these vitamins at a different time of day than the Risedronate. Do not take calcium and vitamin D if you have high levels of calcium in your blood.

• Store at room temperature in a well-closed container. Keep out of the reach of children.

For more information on this medication, please call your doctor, pharmacist or nurse.

SIDE EFFECTS PREVENTION WHAT YOU SHOULD DO
COMMON:
• Nausea, vomiting, diarrhea

• Stomach pain

• Chest pain, heartburn

• Esophageal irritation (difficulty or pain upon swallowing)

• Take tablet with a full glass of water

• Do not lie down for 30 minutes after taking the tablet

• Tell your doctor or nurse if these symptoms bother you

• Tell your doctor or nurse if these become a problem

RARE:
• Mouth irritation

• Muscle pain, Joint pain

• Rash, itching or eye pain

• Swallow tablet whole. Do not chew or split the tablet. • Tell your doctor or nurse if this bothers you.

• One or two regular strength acetaminophen tablets (Tylenol®) may help.

• Tell your doctor or nurse as soon as possible

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