Diagnosis and Therapy

Drugs of abuse

A 50-year-old salesman was admitted to the hospital with acute appendicitis. He has no significant medical history, takes no medications, does not smoke cigarettes, and has an alcoholic beverage “once in a while with the boys.” He underwent…

Drugs of abuse. Class

In addition to alcohol, the major drugs of abuse are nicotine, marijuana (∆9-tetrahydrocannabinol), heroin, and the CNS stimulants, notably cocaine and amphetamine and its derivatives (Table Drugs of abuse). Table: Drugs of abuse NICOTINE MARIJUANA COCAINE/AMPHETAMINE Route of…

Case: Muscarinic cholinomimetic agents. Class

The efferent nerves of the parasympathetic autonomic nervous system release the neurotransmitter ACh at both preganglionic and postganglionic (i.e., “cholinergic”) nerve endings, and also at somatic nerve endings. Nitric oxide is a cotransmitter at many of the parasympathetic…

Case: Muscarinic cholinomimetic agents

A 61-year-old man is noted to have increased intraocular pressure on a routine eye examination. The visual acuity is normal in both eyes. The dilated eye examination reveals no evidence of optic nerve damage. Visual field testing shows…

Case: Muscarinic cholinomimetic agents. Questions – Answers

Questions [1] A 62-year-old woman is noted to have open-angle glaucoma. She inadvertently applies excessive pilocarpine to her eyes. This may result in which of the following? A. Bronchial smooth muscle dilation B. Decreased gastrointestinal motility C. Dilation…

Treatment of Young Children with Mental Conditions

A note to parents There has been recent public concern over reports that increasing numbers of very young children are being prescribed psychotropic medications. Some parents are criticized for giving their children these medications while others are criticized…

Psychotherapy Alone May Help Some Depression Patients

A recent study concludes that cognitive psychotherapy can be just as effective for the treatment of atypical major depression as standard drug therapy with phenelzine sulfate. Researchers at the University of Texas-Southwestern Medical Center at Dallas randomized 108…