Author: Jennifer Bowles

Mesalazine

Drug Approvals (British Approved Name, rINN) Synonyms: 5-ASA; 5-Aminosalicylic Acid; Fisalamine; Mesalatsiini; Mesalazin; Mesalazina; Mesalazinas; Mesalazinum BAN: Mesalazine USAN: Mesalamine INN: Mesalazine [rINN (en)] INN: Mesalazina [rINN (es)] INN: Mésalazine [rINN (fr)] INN: Mesalazinum [rINN (la)] INN: Месалазин…

Epirubicin Hydrochloride

Epirubicin Hydrochloride 2 mg/ml Injection •      The active substance is epirubicin hydrochloride. •      The other ingredients are sodium chloride, water for injections and hydrochloric acid used as a pH adjuster. 1. What Epirubicin Hydrochloride 2 mg/ml Injection is…

Arthrotec (Diclofenac and Misoprostol) for Inflammatory Rheumatic Diseases

Arthrotec is a new product that combines the NSAID diclofenac and the prostaglandin analog misoprostol. The diclofenac component of Arthrotec is responsible for the relief of the symptoms of arthritis. The misoprostol component is responsible for the mucoprotective…

Granisetron Hydrochloride

(British Approved Name Modified, US Adopted Name, rINNM) Drug Nomenclature INNs in main languages (French, Latin, Russian, and Spanish): Synonyms: BRL-43694A; Granisetrón, hidrocloruro de; Granisetron-hydrochlorid; Granisetronhydroklorid; Granisetroni Hydrochloridum; Granisetronihydrokloridi; Granisetrono hidrochloridas BAN: Granisetron Hydrochloride [BANM] USAN: Granisetron Hydrochloride…

Non-steroidal Anti-inflammatory Drugs (NSAIDs): Hepatotoxicity

Hepatotoxic effects range from asymptomatic elevations of serum transaminases and alkaline phosphatase to acute cytolytic, cholestatic, or mixed hepatitis. Reye’s syndrome may occur in children in association with acetylsalicylic acid (ASA) use and a viral illness. Elevated liver…

Drugs: To Use or Not to Use

During each of the past ten years the pharmaceutical industry has produced an average of approximately 400 new products. In the most recent year of record, 1957, the number is said to have been precisely 400, and 51…

Tritec and Helidac for Helicobacter pylori Peptic Ulcer Disease

The most common cause of peptic ulcer disease is a bacterium designated Helicobacter pylori that was first observed in gastric biopsy specimens in 1979 and has since been identified in every human population tested on six continents. The…

Laxatives

Laxatives (purgatives or cathartics) promote defaecation and are used in the treatment of constipation (see below) and for bowel evacuation before investigational procedures, such as endoscopy or radiological examination, or before surgery. Laxatives are frequently used for self-medication….

Cladribine (Single Agent)

Overview Cladribine (Ortho Biotech’s Leustatin, Japananssen-Cilag’s Leustatin/ Leustatine/Leustat, generics; also known as chlorodeoxyadenosine and 2-CDA)  is primarily used to treat hairy-cell leukemia. Cladribine is used much less frequently than fludarabine for chronic lymphocytic leukemia because many more, and…

Vascular Disease of the Bowel

Vascular disorders of the gastrointestinal tract typically present as abdominal pain or bleeding, or both. Several of the disorders that cause bleeding, such as ischemic colitis, angiodysplastic lesions, and vascular-enteric fistulas. Mesenteric vascular insufficiency. The clinical spectrum of…