Author: Jennifer Bowles

Antiarrhythmic drugs

A 62-year-old man is being managed in the intensive care unit following a large anterior wall MI. He has been appropriately managed with oxygen, aspirin, nitrates, and P-adrenergic receptor blockers but has developed recurrent episodes of ventricular tachycardia….

Irritable bowel syndrome (IBS). Epidemiology

Newer pharmacologic agents that mediate neurotransmitter activity may prove useful in the treatment of irritable bowel syndrome. Irritable bowel syndrome (IBS) is a chronic disorder characterized by recurrent symptoms of lower abdominal pain with disturbed defecation and bloating….

Baclofen

(British Approved Name, US Adopted Name, rINN) Drug Nomenclature International Nonproprietary Names (INNs) in main languages (French, Latin, Russian, and Spanish): Synonyms: Aminomethyl Chlorohydrocinnamic Acid; Ba-34647; Baclofeno; Baclofenum; Baklofén; Baklofeeni; Baklofen; Baklofenas BAN: Baclofen USAN: Baclofen INN: Baclofen…

Ellence – Medication for Adjuvant Therapy of Breast Cancer

Brand Name: Ellence Active Ingredient: epirubicin Indication: adjuvant treatment of breast cancer that has spread to local lymph nodes Company Name: Pharmacia & Upjohn Introduction Ellence (pronounced el-LENCE) (epirubicin hydrochloride injection), marketed by Pharamacia &Upjohn, is an anthracycline…

Antisense Oligonucleotides

Overview No antisense oligonucleotides are on the market yet for cancer. Despite the compounds’ high specificity and low toxicity, this drug class has been plagued with disappointing results, such as those reported for ISIS-3521 (Isis Pharmaceuticals/Eli Lilly’s Affinitak)…

OTC Famotidine (Pepcid) for Acid Control

Indication: heartburn and acid indigestion Drug Tradename: Pepcid AC Acid Controller Manufacturer: Johnson & Johnson-Merck Johnson & Johnson-Merck has won the race to bring an H(2)-receptor antagonist to the over-the-counter (OTC) market. The joint pharmaceutical venture has received…

Heartburn in practice

Patient perspectives I’ve been having trouble with heartburn. In fact, it is one of the reasons I wanted to lose weight. I used to get it every once in a while, but then it started to get more…

Pipecuronium Bromide

Drug Nomenclature Synonyms: Bromuro de pipecuronio; Pipecurium Bromide; Pipecuronii Bromidum; Pipecuronio, bromuro de; Pipekuroniumbromid; Pipekuroniumbromidi; RGH-1106 BAN: Pipecuronium Bromide USAN: Pipecuronium Bromide INN: Pipecuronium Bromide [rINN (en)] INN: Bromuro de pipecuronio [rINN (es)] INN: Pipécuronium, Bromure de [rINN…

Hepatitis C

Epidemiology Hepatitis C virus, identified in 1988, is an RNA virus that appears to be responsible for most instances of parenterally transmitted non-A, non-B hepatitis. The virus seems to mutate frequently and appear in many subtypes. Table 49-6…

Rabeprazole

Rabeprazole Sodium (Aciphex Tablets, Delayed-Release 20 Mg) Rabeprazole sodium is a proton-pump inhibitor that suppresses gastric acid secretion by blocking acid (proton) pump within gastric parietal cells. It is indicated in short-term treatment in healing and symptomatic relief…