Antineoplastic agents

Carboplatin Intravenous Infusion

Carboplatin 10mg/ml Intravenous Infusion 1. What Carboplatin Intravenous Infusion is and what it is used for Carboplatin Intravenous Infusion is an anti-cancer medicine in the form of a solution for infusion (a solution which can be given as…

Carmustine

(British Approved Name, US Adopted Name, rINN) Drug Nomenclature International Nonproprietary Names (INNs) in main languages (French, Latin, Russian, and Spanish): Synonyms: BCNU; BiCNU; Carmustina; Carmustinum; Karmustiini; Karmustin; Karmustinas; Karmusztin; NSC-409962; WR-139021 BAN: Carmustine USAN: Carmustine INN: Carmustine…

Tamoxifen: Breast Cancer

THE QUESTION Whether to take tamoxifen and whether to undergo chemotherapy are among the decisions made by women with breast cancer. Do the benefits of these treatments outweigh the risks — specifically the possibility of a stroke? THIS…

Antisense Oligonucleotides

Overview No antisense oligonucleotides are on the market yet for cancer. Despite the compounds’ high specificity and low toxicity, this drug class has been plagued with disappointing results, such as those reported for ISIS-3521 (Isis Pharmaceuticals/Eli Lilly’s Affinitak)…

Amsacrine

(British Approved Name, US Adopted Name, rINN) Drug Nomenclature International Nonproprietary Names (INNs) in main languages (French, Latin, Russian, and Spanish): Synonyms: m-AMSA; Acridinyl Anisidide; Amsacrina; Amsacrinum; Amsakriini; Amsakrin; CI-880; NSC-249992 BAN: Amsacrine USAN: Amsacrine INN: Amsacrine [pINN…

Busulfan

(British Approved Name, rINN) Drug Nomenclature International Nonproprietary Names (INNs) in main languages (French, Latin, Russian, and Spanish): Synonyms: Bussulfam; Busulfaani; Busulfan; Busulfanas; Busulfano; Busulfanum; Busulphan; Buszulfán; CB-2041; GT-41; Myelosan; NSC-750; WR-19508 BAN: Busulfan INN: Busulfan [rINN (en)]…

Imuran Tablets (Azathioprine)

Imuran Tablets Azathioprine 1 What Imuran is and what it is used for Imuran tablets contain a medicine called azathioprine. This belongs to a group of medicines called immunosuppressants. These medicines reduce the activity of your body’s immune…

Azacitidine

(US Adopted Name, rINN) Drug Nomenclature International Nonproprietary Names (INNs) in main languages (French, Latin, Russian, and Spanish): Synonyms: 5-Azacytidine; Azacitidina; Ladakamycin; NSC-102816; U-18496 USAN: Azacitidine INN: Azacitidine [rINN (en)] INN: Azacitidina [rINN (es)] INN: Azacitidine [rINN (fr)]…

Fludarabine/Cyclophosphamide/Mitoxantrone (FCM)

Overview The fludarabine, cyclophosphamide, and mitoxantrone (Serono/Wyeth/Takeda’s Novantrone, Baxter’s Onkotrone, generics) regimen is under investigation in clinical trials and is used as the standard of care in some hospitals in Germany and Spain. Mechanism of Action. •  Fludarabine…

ERLOTINIB

ERLOTINIB (er-LOE-tye-nib) Other Names for this Medication (Brand Name): Tarceva Appearance White, round tablet containing 25mg, 100mg or 150mg of Erlotinib. Why this Medication is Used Erlotinib is used to treat certain types of non-small cell lung cancer…